The below tool is a resource you can use to calculate a patient’s Creatinine Clearance (CrCl) using the patient’s gender, their actual body weight (in kilograms), and their Serum Creatinine levels (in mg/dL).
This calculator uses the Cockcroft-Gault equation. All calculations should be confirmed and reassessed before use.
Based on the parameters provided, this patient's creatinine clearance (CrCl) is mL/min.
Administer AGGRASTAT intravenously 25 mcg/kg within 5 minutes and then mcg/kg/min for up to 18 hours.
Download the Dosing & Administration Guide for AGGRASTAT®
A dose adjustment is required for patients with severe renal insufficiency (defined as creatinine clearance <60 mL/min). For these patients, reduce the maintenance infusion of AGGRASTAT to 0.075 mcg/kg/min for up to 18 hours. The bolus dose is not adjusted. Creatinine Clearance is calculated using the Cockcroft-Gault equation.
This calculator uses the Cockcroft-Gault equation. All calculations should be confirmed and reassessed before use. By using this resource, you agree to the following: This calculator is being provided “AS IS” and is intended for use only by qualified healthcare providers. All calculations should be confirmed before use. Medicure makes no claims as to the accuracy of the information contained herein. The information being provided is not a substitute for clinical judgment. Neither Medicure, nor any other party involved in the preparation or publication of this site, shall be liable to you or others for any decisions made or actions taken by you or others in reliance on this information.
Aggrastat® is indicated to reduce the rate of thrombotic cardiovascular events (combined endpoint of death, myocardial infarction, or refractory ischemia/repeat cardiac procedure) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS).